姓名：张雪琼
性别：女
出生年月：1982年2月
学历／学位：博士研究生
职称：副教授
Email:zhangxq@whut.edu.cn
教育经历
2007/09-2010/12，5845威尼斯官网主页，材料科学与工程学院
2003/09-2006/09，湖北中医药大学，药学院，硕士
1999/09-2003/09，湖北中医药大学，药学院，学士
研究经历
2016/06-2017/06，美国北卡罗来纳大学教堂山分校，访问学者，合作导师 Leaf Huang。
2014/09-至今，5845威尼斯官网主页，5845威尼斯官网主页制药工程系，副教授
2011/05-2014/09，5845威尼斯官网主页，5845威尼斯官网主页制药工程系，讲师
研究领域
药物新剂型、天然药物化学
代表性科研项目
1.健脾生血颗粒（片）药效学及效应物质研究 80万元
2.湖北省校企共建现代中药研发中心 25万元
3.壳聚糖改性材料的研究 20万元
代表性论文与专著
1. Co-delivery of rose bengal and doxorubicin nanoparticles for combination photodynamic and chemo-therapy. Journal of biomedical nanotechnology, 2019, 15: 184-195.
2. Nanotechnology: a promising method for oral cancer detection and diagnosis. Journal of nanobiotechnology, 2018, 16: 52-68.
3. Nanoparticle-mediated trapping of Wnt family member 5A in tumor microenvironments enhances immunotherapy for B-Raf proto-oncogene-mutant melanoma, ACS Nano, 2018, 12(2): 1250-1261.
4. Nano-delivery of fraxinellone remodels tumor microenvironment and facilitates therapeutic vaccination in desmoplastic melanoma. Theranostics, 2018, 8(14): 3781-3796.
5.Cisplatin-crosslinked glutathione-sensitive micelles loaded with doxorubicin for combination and targeted therapy of tumors. Carbohydrate Polymers 2017, 155: 407-415.
6.A pH-Sensitive Nanosystem Based on carboxymethyl chitosan for tumor-targeted delivery of daunorubicin. Journal of biomedical nanotechnology, 2016, 12(8): 1688-1698.
7.Glutathione-dependent micelles based on carboxymethyl chitosan for delivery of doxorubicin. Journal of biomaterials ccience-polymer edition, 2016, 27(18):1824-1840.
8.Self-assembled nanoparticles based on folic acid modified carboxymethyl chitosan conjugated with targeting antibody, Journal of wuhan university of technology-materials science edition, 2016, 31(2): 446-453.
9. pH/redox responsive core cross-linked nanoparticles from thiolated carboxymethyl chitosan for in vitro release study of methotrexate, Carbohydrate polymers, 2014, 111(20): 964-970.
获得学术奖励
基于多学科组合技术的健脾生血颗粒深度开发, 湖北省科技厅, 湖北省科技进步奖, 二等奖, 2016